Multimodality Imaging for Left Ventricular Hypertrophy Severity Grading: A Methodological Review

Multimodality imaging for pre-clinical assessment of Fabry's cardiomyopathy.

Anderson Fabry's disease (AFD) is a rare but underdiagnosed intracellular lipid disorder which can cause left ventricular hypertrophy (LVH). Pre-clinical diagnosis of Fabry's disease is important as it permits early stratification for enzyme replacement therapy, improving the patient's long-term prognosis, avoiding progression to irreversible fibrosis, and preventing cardiovascular complication...

The left ventricle in aortic stenosis – imaging assessment and clinical implications

Aortic stenosis has an increasing prevalence in the context of aging population. In these patients non-invasive imaging allows not only the grading of valve stenosis severity, but also the assessment of left ventricular function. These two goals play a key role in clinical decision-making. Although left ventricular ejection fraction is currently the only left ventricular function parameter that...

Evidence for Left Ventricular Outflow Tract Obstruction With Minimal Septal Hypertrophy: The Case Grows Stronger for a Multimodality Imaging Strategy for Hypertrophic Cardiomyopathy.

Multimodality imaging in apical hypertrophic cardiomyopathy.

Apical hypertrophic cardiomyopathy (AHCM) is a relatively rare morphologic variant of HCM in which the hypertrophy of myocardium is localized to the left ventricular apex. Symptoms of AHCM might vary from none to others mimic coronary artery disease including acute coronary syndrome, thus resulting in inappropriate hospitalization. Transthoracic echocardiography is the first-line imaging techni...

Aortic Stenosis, a Left Ventricular Disease: Insights from Advanced Imaging

Aortic stenosis (AS) is the most common primary valve disorder in the elderly with an increasing prevalence. It is increasingly clear that it is also a disease of the left ventricle (LV) rather than purely the aortic valve. The transition from left ventricular hypertrophy to fibrosis results in the eventual adverse effects on systolic and diastolic function. Appropriate selection of patients fo...